8-(3-Bromo-5-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane CAS 1506296-07-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1506296-07-6
Molecular FormulaC14H17BrFNO2
Molecular Weight330.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-(3-Bromo-5-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane CAS 1506296-07-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-(3-Bromo-5-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane.

8-(3-Bromo-5-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 1506296-07-6), molecular formula C14H17BrFNO2 and molecular weight 330.19 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 8-(3-Bromo-5-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane (C14H17BrFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 330.19 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 8-(3-Bromo-5-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H17BrFNO2
Molecular Weight330.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF/Br-containing
Nitrogen Atoms1

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