Tert-butyl (2R,3S)-3-(hydroxymethyl)-2-(pyridin-3-yl)pyrrolidine-1-carboxylate CAS 150663-79-9
| CAS No. | 150663-79-9 |
| Molecular Formula | C15H22N2O3 |
| Molecular Weight | 278.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tert-butyl (2R,3S)-3-(hydroxymethyl)-2-(pyridin-3-yl)pyrrolidine-1-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tert-butyl (2R,3S)-3-(hydroxymethyl)-2-(pyridin-3-yl)pyrrolidine-1-carboxylate (CAS 150663-79-9), molecular formula C15H22N2O3 and molecular weight 278.35 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Tert-butyl (2R,3S)-3-(hydroxymethyl)-2-(pyridin-3-yl)pyrrolidine-1-carboxylate (C15H22N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 278.35 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl (2R,3S)-3-(hydroxymethyl)-2-(pyridin-3-yl)pyrrolidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H22N2O3 |
| Molecular Weight | 278.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 2 |
Recommended Standards
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- Ethyl [4-Oxo-4-(phenethylamino)butyl]carbamate (CAS 1477949-42-0)
- N-(2-Ethylhexyl)-4-nitrobenzamide (CAS 154702-08-6)
- 1-((5-Methyl-2-(3-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)pyrrolidin-3-amine (CAS 1332199-28-6)
- 3-Bromochlorobenzene (CAS 108-37-2)
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