Minodronic Impurity 22 CAS 1507308-67-9
| CAS No. | 1507308-67-9 |
| Molecular Formula | C9H7ClN2O2 |
| Molecular Weight | 210.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Minodronic Impurity 22 (CAS 1507308-67-9, C9H7ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Minodronic Impurity 22 (C9H7ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 210.62 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Minodronic Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClN2O2 |
| Molecular Weight | 210.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Minodronic Standards
- Minodronic Impurity 1 (CAS 21755-34-0)
- Minodronic Impurity 28 (CAS CATO-C4X-124128)
- Minodronic Impurity 34 (CAS 164733-64-6)
- Minodronic Impurity 11 (CAS 653599-20-3)
- Minodronic Acid Impurity 3 (CAS 1260383-71-8)
- Minodronic Acid Impurity 9 (CAS 1244029-51-3)
- Minodronic Acid Impurity 20 (CAS CATO-C4X-124120)
- Minodronic Acid Impurity 14 (CAS CATO-C4X-124114)
Recommended Standards
- 5-(2-chlorophenyl)imidazolidine-2,4-dione (CAS 103029-09-0)
- 4-Chloro-6-(difluoromethyl)-2-(methylthio)pyrimidine (CAS 1204298-68-9)
- Chloro-7-azaindole-4-carboxylic acid methyl ester (CAS 1015609-99-0)
- 1-Chloro-6-fluoro-3,4-dihydronaphthalene-2-carbaldehyde (CAS 1422683-87-1)
- Fluvoxamine impurity 48 (CAS CATO-C4X-195148)
- Albendazole Impurity N78 (CAS 139751-05-6)
- Pregabalin Impurity 63 (CAS 7214-61-1)
- 1-(2-(Indolin-1-yl)-2-oxoethyl)-2-methyl-1H-indole-3-carbaldehyde (CAS 433963-38-3)
- 2-Bromo-5-methoxy-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)benzamide (CAS 1396854-81-1)
- Dimethyl 4,5-dimethylphthalate (CAS 17649-59-1)
- methyl 2-(1H-triazol-5-yl)acetate (CAS 1092286-86-6)
- 1-(2-(Butylamino)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1250908-78-1)
- 1-(Benzo[b]thiophen-5-yl)-N-methylmethanamine (CAS 934993-63-2)
- Peptide Impurity 34 (CAS 21282-09-7)
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