5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite CAS 150780-67-9
| CAS No. | 150780-67-9 |
| Molecular Formula | C45H56N7O9P |
| Molecular Weight | 869.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (CAS 150780-67-9) is a high-purity analytical reference standard with the molecular formula C45H56N7O9P and a molecular weight of 869.94 g/mol.
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (C45H56N7O9P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C45H56N7O9P |
| Molecular Weight | 869.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 7 |
Related O Standards
- 5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-dG(N-iBu)-3'-CEDPA 93183-15-4 deoxyguanosine-ce phosphoramidite*for cyclone dmt-dg(dmf) amidite 2g 89 12 pack dmt-dg(dmf) amidite 5g, single dmt-dg(ib) amidite 2g ab 12 pack dmt-dg(ib) amidite 5g single dna g phosphoramidite (CAS 93183-15-4)
- 330628-04-1 5'-O-(4,4'-dimethoxytrityl)-N-dimethyl-formamidine-2'-deoxyguanosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite 5'-O-(4,4'-dimethoxytrityl)-N-dimethyl-formamidine-2'-deoxyguanosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; EBD296414 N2-dimethylformamidine-2'-deoxyguanosine-3'-diisopropylaminocyanoethyl phosphoramidite (CAS 330628-04-1)
- N-(16-(Dimethoxytrityl)oxy-15-hydroxy-4,7,10,13-tetraoxahexadecyl)-D-(+)-biotinamide (CAS 869354-57-4)
- N-(4,4-Dimethoxytrityl)-8-bromoguanosine 2,3,5-Triacetate (CAS 1096020-93-7)
- N-(4,4-Dimethoxytrityl)-8-nitroguanosine 2,3,5-Triacetate (CAS 1096020-94-8)
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