1-bromo-3-(chloromethyl)-2,4-difluorobenzene CAS 1507849-24-2
| CAS No. | 1507849-24-2 |
| Molecular Formula | C7H4BrClF2 |
| Molecular Weight | 241.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-bromo-3-(chloromethyl)-2,4-difluorobenzene is closely related to fluorine/chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-bromo-3-(chloromethyl)-2,4-difluorobenzene (CAS 1507849-24-2) is a high-purity analytical reference standard with the molecular formula C7H4BrClF2 and a molecular weight of 241.46 g/mol.
Owing to fluorine/chlorine/bromine substitution, an aromatic ring system, 1-bromo-3-(chloromethyl)-2,4-difluorobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4BrClF2 |
| Molecular Weight | 241.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl/Br-containing |
Related bromo Standards
- 1-Bromo-3-(chloromethyl)-2,5-difluorobenzene (CAS 1159186-57-8)
- 3-Bromo-2-chloro-4,5-difluorotoluene (CAS 1208077-47-7)
- 1-Bromo-3-chloro-2-(difluoromethyl)benzene (CAS 1214348-94-3)
- 4-Bromo-2-chloro-1-(difluoromethyl)benzene (CAS 1254034-23-5)
- 5-Bromo-2,4-difluorobenzyl chloride (CAS 1260810-32-9)
- 2-Bromo-4-chloro-1-(difluoromethyl)benzene (CAS 1261476-50-9)
- 2-Bromo-1-chloro-4-(difluoromethyl)benzene (CAS 1261495-96-8)
- 1-Bromo-3-chloro-5-(difluoromethyl)benzene (CAS 1261580-23-7)
Recommended Standards
- 5-(Bromomethyl)-2-chloro-1,3-difluorobenzene (CAS 1400991-56-1)
- 2-Bromo-4-(chloromethyl)-1,3-difluorobenzene (CAS 1515891-41-4)
- 6-Chloro-2,3-difluorobenzyl bromide (CAS 1373921-07-3)
- 1-Bromo-4-chloro-3-fluoro-2-(fluoromethyl)benzene (CAS 1628524-82-2)
- (R)-3-(Cbz-amino)-2-piperidone (CAS 722499-65-2)
- 6-Iodo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 1203499-25-5)
- Ethyl 2-cyclohexylpyrimidine-5-carboxylate (CAS 1447606-84-9)
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- 4-(3-Chlorophenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1192691-11-4)
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