1508250-72-3 67HTX614WR Nazartinib mesylate UNII-67HTX614WR 4-Pyridinecarboxamide, N-(7-chloro-1-((3R)-1-((2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl)hexahydro-1H-azepin-3-yl)-1H-benzimidazol-2-yl)-2-methyl-, methanesulfonate (1:1) EGF-816 mesylate CAS 1508250-72-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1508250-72-3
Molecular FormulaC26H31ClN6O2
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1508250-72-3
67HTX614WR
Nazartinib mesylate
UNII-67HTX614WR
4-Pyridinecarboxamide, N-(7-chloro-1-((3R)-1-((2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl)hexahydro-1H-azepin-3-yl)-1H-benzimidazol-2-yl)-2-methyl-, methanesulfonate (1:1)
EGF-816 mesylate CAS 1508250-72-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 591.12 g/mol gives 1508250-72-3 67HTX614WR Nazartinib mesylate UNII-67HTX614WR 4-Pyridinecarboxamide, N-(7-chloro-1-((3R)-1-((2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl)hexahydro-1H-azepin-3-yl)-1H-benzimidazol-2-yl)-2-methyl-, methanesulfonate (1:1) EGF-816 mesylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1508250-72-3 67HTX614WR Nazartinib mesylate UNII-67HTX614WR 4-Pyridinecarboxamide, N-(7-chloro-1-((3R)-1-((2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl)hexahydro-1H-azepin-3-yl)-1H-benzimidazol-2-yl)-2-methyl-, methanesulfonate (1:1) EGF-816 mesylate (CAS 1508250-72-3) is a high-purity analytical reference standard with the molecular formula C26H31ClN6O2CH4O3S and a molecular weight of 591.12 g/mol.

Structurally, 1508250-72-3 67HTX614WR Nazartinib mesylate UNII-67HTX614WR 4-Pyridinecarboxamide, N-(7-chloro-1-((3R)-1-((2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl)hexahydro-1H-azepin-3-yl)-1H-benzimidazol-2-yl)-2-methyl-, methanesulfonate (1:1) EGF-816 mesylate (C26H31ClN6O2CH4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 591.12 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC26H31ClN6O2 CH4O3S
Molecular Weight591.12 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentCl-containing
Nitrogen Atoms6
Sulfur Atoms1

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