Fmoc-L-thyroxine CAS 151889-56-4
| CAS No. | 151889-56-4 |
| Molecular Formula | C30H21I4NO6 |
| Molecular Weight | 999.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fmoc-L-thyroxine.
Fmoc-L-thyroxine (CAS 151889-56-4), molecular formula C30H21I4NO6 and molecular weight 999.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Fmoc-L-thyroxine (C30H21I4NO6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Fmoc-L-thyroxine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H21I4NO6 |
| Molecular Weight | 999.11 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- Fmoc-D-thyroxine (CAS 1217630-45-9)
- Fmoc-His(Trt)-His(Trt)-OH (CAS CATO-CPTD788602)
- 384346-85-4 N-Fmoc-4,6-benzylidene-2'3'4'6'-tetra-O-acetyl T Epitope, Threonyl Allyl Ester N-Fmoc-O-[2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-|A-D-galactopyranosyl)-|A-D-galactopyranosyl]-L-threonine Allyl Ester (CAS 384346-85-4)
- FMoc-ala-ala-asn(trt)-pab-pnp (CAS 1438853-39-4)
- Fmoc-Lys(Mtt)-Lys(Mtt)-OH (CAS CATO-CPTD789020)
- Fmoc-Gln(Trt)-Gln(Trt)-OH (CAS CATO-CPTD788297)
- Fmoc-Gln(Trt)-Gln(Trt)-OH (CAS CATO-CPTD788473)
- Fmoc-L-N-Me-Asn(Trt)-L-N-Me-Asn(Trt)-OH (CAS CATO-CPTD788996)
Recommended Standards
- [Asu1,6,Arg8] Vasotocin (CAS 35375-13-4)
- 4,8-Bis(5-(2-ethylhexyl)-4-hexylthiophen-2-yl)-2,6-diiodobenzo[1,2-b:4,5-b']dithiophene (CAS 1642807-86-0)
- Cy5.5-Azide (CAS 1955527-41-9)
- 5,12-Dibromo-2,9-Bis(2-hexyldecyl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,3aH,9H,12H)-tetraone (CAS 2733830-29-8)
- 4-((2,2-Difluorocyclopropyl)methoxy)benzaldehyde (CAS 1707562-77-3)
- ((1,4-Diazabicyclo[2.2.2]octan-1-ium-1-yl)sulfonyl)(tert-butoxycarbonyl)amide (CAS 1375958-75-0)
- N-Methyl-1-[1-(3-methylphenyl)-1H-pyrazol-4-yl]methanamine hydrochloride (CAS 1049765-34-5)
- Mix 1,4-dichlorobenzene-d4 chlorobenzene-d5 and fluorobenzene (CAS CATO-MCHM702895-ME)
- 2-Chlorofuro[2,3-b]pyridine (CAS 2089311-13-5)
- 3-(o-Tolyl)isoxazole (CAS 1093649-60-5)
- 3-(5-Fluoropyridin-2-yl)thiazolidine (CAS 1707358-04-0)
- 2-((Adamantan-1-ylmethyl)amino)ethan-1-ol (CAS 65738-69-4)
- 1-(4-Methoxybenzyl)-1H-pyrrole-2,5-dione (CAS 140480-96-2)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com