1-Methyl-2-(trifluoromethyl)-1H-benzo[d]imidazole-4-carbonitrile CAS 1519218-26-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1519218-26-8
Molecular FormulaC10H6F3N3
Molecular Weight225.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Methyl-2-(trifluoromethyl)-1H-benzo[d]imidazole-4-carbonitrile CAS 1519218-26-8 chemical structure

Description

The molecular framework of 1-Methyl-2-(trifluoromethyl)-1H-benzo[d]imidazole-4-carbonitrile (C10H6F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies 1-Methyl-2-(trifluoromethyl)-1H-benzo[d]imidazole-4-carbonitrile (CAS 1519218-26-8), a certified reference material (molecular formula C10H6F3N3, MW 225.17 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-Methyl-2-(trifluoromethyl)-1H-benzo[d]imidazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H6F3N3
Molecular Weight225.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms3

Related Methyl Standards

Recommended Standards

Why CATO?