Epothilone B CAS 152044-54-7
| CAS No. | 152044-54-7 |
| Molecular Formula | C27H41NO6S |
| Molecular Weight | 507.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Epothilone B (CAS 152044-54-7, C27H41NO6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Epothilone B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 507.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Epothilone B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H41NO6S |
| Molecular Weight | 507.68 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Epothilone Standards
Recommended Standards
- Fimasartan-d6 (CAS 247257-48-3 (unlabeled))
- Bempedoic Acid Impurity 34 (CAS CATO-C4X-218934)
- C18(Plasm) LPC (CAS 97802-55-6)
- Fexofenadine-D6 (CAS 548783-71-7)
- Lornoxicam impurity 69 (CAS CATO-C4X-201669)
- Baricitinib Impurity 55 (CAS CATO-C4X-226055)
- Pitavastatin Impurity 77 (CAS 167934-30-7)
- 1,10-Phenanthroline-4-carbaldehyde (CAS 31301-30-1)
- 2-(3,4,5-Trimethoxyphenyl)propan-2-amine (CAS 1176702-49-0)
- 8-Bromo-2-chloro-5-methoxyquinoline-3-carbaldehyde (CAS 1259319-35-1)
- 2-(4-(Pyrrolidin-1-ylsulfonyl)phenyl)ethan-1-amine hydrochloride (CAS 1224170-51-7)
- 1-Heptandecanoyl-3-chloropropanediol (CAS 87505-04-2)
- 6-(4-Bromophenyl)-4-hydrazinylthieno[3,2-d]pyrimidine (CAS 848369-58-4)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com