2-(4-Chlorophenoxy)-5-fluoroaniline CAS 15212-01-8
| CAS No. | 15212-01-8 |
| Molecular Formula | C12H9ClFNO |
| Molecular Weight | 237.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(4-Chlorophenoxy)-5-fluoroaniline (CAS 15212-01-8) is a high-purity analytical reference standard with the molecular formula C12H9ClFNO and a molecular weight of 237.66 g/mol.
2-(4-Chlorophenoxy)-5-fluoroaniline (C12H9ClFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H9ClFNO |
| Molecular Weight | 237.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenoxy Standards
- 2-(2-Chlorophenoxy)-5-fluoroaniline (CAS 946774-87-4)
- 2-(3-Chlorophenoxy)-5-fluoroaniline (CAS 946716-93-4)
- 4-(2-Chlorophenoxy)-3-fluoroaniline (CAS 946785-59-7)
- 4-(3-Chlorophenoxy)-3-fluoroaniline (CAS 946699-10-1)
- 4-(4-Chlorophenoxy)-3-fluoroaniline (CAS 946664-06-8)
- 4-((4-Chlorophenoxy)methyl)-3,5-dimethylisoxazole (CAS 303985-56-0)
- 5-(2-Chlorophenoxy)furan-2-carboxylic acid (CAS 1082119-89-8)
- 5-(3-Chlorophenoxy)furan-2-carboxylic acid (CAS 1248668-43-0)
Recommended Standards
- (3-Chloro-5-fluoropyridin-2-yl)(phenyl)methanol (CAS 1443349-71-0)
- 3-(Benzyloxy)-5-chloro-2-fluoropyridine (CAS 1616667-42-5)
- (4-Chloro-3-fluoropyridin-2-yl)(phenyl)methanol (CAS 1443348-80-8)
- 6-(Benzyloxy)-3-chloro-2-fluoropyridine (CAS 1817717-64-8)
- 2-(Thiophen-2-yl)pyrimidine-5-carboxylic acid (CAS 916766-97-7)
- 5-(Methoxymethyl)isoxazol-3-amine hydrochloride (CAS 1820615-29-9)
- 4-Methyl-N-(piperidin-3-yl)benzenesulfonamide hydrochloride (CAS 1581618-25-8)
- 4-(3-(4-(2,4-Diamino-6-methylpyrimidin-5-yl)benzyl)ureido)-2-methylbenzene-1-sulfonyl fluoride (CAS 50699-49-5)
- (3S,4S,5R)-Tetrahydro-2H-pyran-2,3,4,5-tetraol (CAS 10257-34-8)
- Methyl 6-aminocyclohex-3-ene-1-carboxylate hydrochloride (CAS 1987680-47-6)
- [2-Methyl-3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]amine (CAS 292058-54-9)
- (E)-1-Chloro-1,1-difluoro-4-{[2-(1H-indol-3-yl)ethyl]amino}-3-buten-2-one (CAS 478047-13-1)
- Chloroethynylbenzene (CAS 42553-93-5)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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