6-Oxo-4-(trifluoromethyl)piperidine-3-carboxylic acid CAS 1521399-36-9
| CAS No. | 1521399-36-9 |
| Molecular Formula | C7H8F3NO3 |
| Molecular Weight | 211.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Oxo-4-(trifluoromethyl)piperidine-3-carboxylic acid (C7H8F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-Oxo-4-(trifluoromethyl)piperidine-3-carboxylic acid (CAS 1521399-36-9) is a high-purity analytical reference standard with the molecular formula C7H8F3NO3 and a molecular weight of 211.14 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Oxo-4-(trifluoromethyl)piperidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8F3NO3 |
| Molecular Weight | 211.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Oxo Standards
- 2-oxo-6-(trifluoromethyl)piperidine-3-carboxylic acid (CAS 1031130-72-9)
- 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 1256807-20-1)
- 4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzonitrile (CAS 128886-91-9)
- 3-(Trifluoromethyl)imidazo[1,5-a]pyridine-1-carbonitrile (CAS 1785321-90-5)
- 3-(Trifluoromethyl)benzofuran-5-carbonitrile (CAS 1823954-84-2)
- 2-(Trifluoromethyl)-1H-benzo[d]imidazole-5-carbonitrile (CAS 3671-61-2)
- 2-[5-(trifluoromethyl)pyridin-2-yl]propanedinitrile (CAS 377760-12-8)
- 6-(Trifluoromethyl)-1H-indazole-3-carbonitrile (CAS 887577-45-9)
Recommended Standards
- n-Allyl-n-(2,2,2-trifluoroacetyl)glycine (CAS 1501030-03-0)
- (R)-1-(2,2,2-Trifluoroacetyl)pyrrolidine-2-carboxylic acid (CAS 134454-19-6)
- 4-(Cyanomethyl)-5-(difluoromethyl)-3-fluoropicolinonitrile (CAS 1804491-58-4)
- 2-(1-(2,2,2-Trifluoroacetyl)azetidin-3-yl)acetic acid (CAS 1343927-06-9)
- Ethyl Indazole-5-carboxylate (CAS 192944-51-7)
- 3-Chloro-5-fluoropicolinic acid (CAS 128073-01-8)
- N1-Benzyl-N2-isopropylethane-1,2-diamine (CAS 57857-10-0)
- 1-Chloro-3,5-dimethyl-2-nitrobenzene (CAS 124421-11-0)
- 5-Bromo-2-chlorophenoxy(tert-butyl)dimethylsilane (CAS 1881291-40-2)
- (R)-2-((tert-Butoxycarbonyl)amino)-2-(3-chlorophenyl)acetic acid (CAS 926641-28-3)
- Methyl 4-acetamido-2-(3-methylbenzoyloxy)benzoate (CAS 477889-94-4)
- 2-(4-Aminophenyl)pyrimidine-5-carbonitrile (CAS 1379303-16-8)
- Triptotriterpenic acid C (CAS 123914-32-9)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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