(R)-1-(4-chlorophenyl)ethane-1,2-diol CAS 152142-03-5
| CAS No. | 152142-03-5 |
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (R)-1-(4-chlorophenyl)ethane-1,2-diol (CAS 152142-03-5), a certified reference material (molecular formula C8H9ClO2, MW 172.61 g/mol) for analytical method development and quality control.
The molecular framework of (R)-1-(4-chlorophenyl)ethane-1,2-diol (C8H9ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
Related R Standards
- (S)-1-(2-Chlorophenyl)-1,2-ethanediol (CAS 133082-13-0)
- (S)-1-(3-Chlorophenyl)ethane-1,2-diol (CAS 152008-72-5)
- (R)-1-(2-Chlorophenyl)ethane-1,2-diol (CAS 32345-65-6)
- (R)-1-(3-Chlorophenyl)-1,2-ethanediol (CAS 80051-04-3)
- S-(4-chlorophenyl) methanethioate (CAS 27064-05-7)
- 1-(4-Chlorophenyl)-2-fluoroethanone (CAS 329-78-2)
- (E)-3-(4-chlorophenyl)acrylaldehyde 4-Chloro cinnamaldehyde 49678-02-6 (CAS 49678-02-6)
- 1-(2-Chlorophenyl)ethane-1-thiol (CAS 1016716-81-6)
Recommended Standards
- 2-Chloro-1-(1-ethyl-1h-pyrazol-4-yl)ethan-1-one (CAS 1536255-49-8)
- 2-((3-Chloropyridin-4-yl)oxy)ethan-1-amine (CAS 1505185-58-9)
- 2-(2-Chlorophenoxy)ethanol (CAS 15480-00-9)
- 3-Chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-ol (CAS 1451184-45-4)
- Ethyl 2,3-dibromopyridine-4-acetate (CAS 1807035-01-3)
- 5-(4-Chlorophenoxy)-1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde (CAS 109925-44-2)
- 5-Cyclopropyl-morpholin-3-one (CAS 1260667-89-7)
- Monomethyl Isophthalate (CAS 1877-71-0)
- 6-(4-Ethylpiperazin-1-yl)-4-methylnicotinonitrile (CAS 1355179-57-5)
- 2-tert-Butyl-5-chloro-1,3,4-thiadiazole (CAS 77822-86-7)
- (R)-3-Piperidinemethanol Hydrochloride (CAS 1124199-58-1)
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- N-(4-acetylphenyl)-2-(4-chloro-2-methylphenoxy)propanamide (CAS 14157-43-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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