4-Bromo-2-fluoro-5-iodobenzoic acid CAS 1521585-65-8
| CAS No. | 1521585-65-8 |
| Molecular Formula | C7H3BrFIO2 |
| Molecular Weight | 344.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Bromo-2-fluoro-5-iodobenzoic acid (CAS 1521585-65-8) is a high-purity analytical reference standard with the molecular formula C7H3BrFIO2 and a molecular weight of 344.90 g/mol.
The molecular framework of 4-Bromo-2-fluoro-5-iodobenzoic acid (C7H3BrFIO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 4-Bromo-2-fluoro-5-iodobenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3BrFIO2 |
| Molecular Weight | 344.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br/I-containing |
Related Bromo Standards
- 2-Bromo-6-fluoro-4-iodobenzoic acid (CAS 1260382-05-5)
- 2-Bromo-4-fluoro-5-iodo-benzoic acid (CAS 1263378-34-2)
- 5-Bromo-3-fluoro-2-iodobenzoic acid (CAS 1335511-41-5)
- 5-Bromo-4-fluoro-2-iodobenzoic acid (CAS 1335513-63-7)
- 2-bromo-4-fluoro-6-iodobenzoic acid (CAS 1421275-39-9)
- 5-Bromo-2-fluoro-3-iodobenzoic acid (CAS 1517342-25-4)
- 3-Bromo-4-fluoro-5-iodobenzoic acid (CAS 1628539-97-8)
- 5-Bromo-2-fluoro-4-iodobenzoic acid (CAS 1807757-08-9)
Recommended Standards
- 4-Bromo-2-fluoro-3-iodobenzoic acid (CAS 1809157-98-9)
- 4-bromo-3-fluoro-2-iodobenzoic acid (CAS 1823316-00-2)
- 4-Bromo-5-fluoro-2-iodobenzoic acid (CAS 1870155-80-8)
- 4-Bromo-2-fluoro-6-iodobenzoic acid (CAS 1936243-93-4)
- 2-(Ethylthio)nicotinamide (CAS 175135-27-0)
- 2-Bromo-4-(2,2,2-trifluoroethoxy)pyridine (CAS 1628553-37-6)
- N-(4-Bromo-2,6-dichloro-3-methylphenyl)acetamide (CAS 68399-95-1)
- 2-((4-Methoxybenzyl)thio)-7-methyl-4H-pyrido[1,2-a][1,3,5]triazin-4-one (CAS 306979-23-7)
- 4-Cyclopentylphenol (CAS 1518-83-8)
- n-((4-Methylmorpholin-2-yl)methyl)cyclopentanamine (CAS 1495770-11-0)
- 9H-Carbazole-3-carbaldehyde (CAS 51761-07-0)
- Benzyl N-(4-nitrophenyl)carbamate (CAS 53821-12-8)
- Brivaracetam Impurity 171 (CAS CATO-C4X-2007171)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com