(S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one CAS 1523404-29-6
| CAS No. | 1523404-29-6 |
| Molecular Formula | C18H25F3N4O3 |
| Molecular Weight | 402.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one (CAS 1523404-29-6), a certified reference material (molecular formula C18H25F3N4O3, MW 402.41 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 402.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H25F3N4O3 |
| Molecular Weight | 402.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- GCN2-IN-1 (CAS 1448693-69-3)
- 1-tert-Butyl-4-(2-{[3-(trifluoromethyl)phenyl]methoxy}benzoyl)-1H-pyrazole (CAS 956782-88-0)
- 2,4-Dibromo-3-trifluoromethylbenzenesulfonyl chloride (CAS 1349715-91-8)
- 2-(4-(1H-Benzo[d]imidazol-2-yl)piperidin-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 605626-30-0)
- 5-(6-Formylpyridin-2-yl)thiophene-2-carboxylic acid (CAS 656227-41-7)
- 2-((4-Chloropyridin-2-yl)oxy)acetic acid (CAS 89692-15-9)
- N,N,3-Trimethylpiperidin-4-amine (CAS 396133-23-6)
- 1,3-Dimethyl-4-((methylamino)methylene)-1H-pyrazol-5(4H)-one (CAS 41106-20-1)
- 8-((5,6,7,8-Tetrahydronaphthalen-2-yl)sulfonyl)-8-azabicyclo[3.2.1]oct-2-ene (CAS 1798047-09-2)
- 1'-Methyl-1'H-spiro[piperidine-4,4'-quinolin]-2'(3'H)-one (CAS 167484-43-7)
- 5-(2-(2-(4-(3-(Dimethylamino)propoxy)phenyl)propan-2-yl)pyridin-4-yl)-4-methylthiazol-2-amine (CAS 1395492-87-1)
- 1-(2-Amino-4-(trifluoromethyl)thiazol-5-yl)ethanone 4-methylbenzenesulfonate (CAS 1377581-60-6)
- 5-Benzyl-4,5-dihydro-1H-imidazol-2-amine (CAS 94830-58-7)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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