4-(2-Chloro-6-fluorobenzyl)piperidine hydrochloride CAS 1523618-16-7
| CAS No. | 1523618-16-7 |
| Molecular Formula | C12H15ClFN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(2-Chloro-6-fluorobenzyl)piperidine hydrochloride (CAS 1523618-16-7) is a high-purity analytical reference standard with the molecular formula C12H15ClFNHCl and a molecular weight of 264.17 g/mol.
Structurally, 4-(2-Chloro-6-fluorobenzyl)piperidine hydrochloride (C12H15ClFNHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 264.17 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15ClFN HCl |
| Molecular Weight | 264.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- N-Acetyl-DL-penicillamine (CAS 59-53-0)
- (E)-1-(3-bromoprop-1-en-1-yl)-4-(trifluoromethyl)benzene (CAS 762247-01-8)
- 4-Hexyl-3-iodobenzoic acid (CAS 1131614-31-7)
- 1-Bromo-4-chloro-3-(difluoromethyl)-2-fluorobenzene (CAS 943830-37-3)
- 2,2-Difluoro-2-(3-methoxypyridin-2-yl)acetic acid (CAS 1698403-23-4)
- 4-Bromo-2-chloro-1-(vinyloxy)benzene (CAS 869569-67-5)
- 2-Amino-3-sulfopropanoic acid hydrochloride (CAS 20244-18-2)
- Methyl 3-(4-bromophenyl)-3-(4-methoxybenzenesulfonamido)propanoate (CAS 383148-23-0)
- N-(2-Phenylethyl)but-3-en-1-amine (CAS 867324-06-9)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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