6-(((4-((1H-Indol-1-yl)sulfonyl)phenyl)(prop-2-yn-1-yl)amino)methyl)-2-methylquinazolin-4(3H)-one CAS 152503-91-8

Purity 97%+In StockPharmaceutical Standards
CAS No.152503-91-8
Molecular FormulaC27H22N4O3S
Molecular Weight482.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(((4-((1H-Indol-1-yl)sulfonyl)phenyl)(prop-2-yn-1-yl)amino)methyl)-2-methylquinazolin-4(3H)-one CAS 152503-91-8 chemical structure

Description

6-(((4-((1H-Indol-1-yl)sulfonyl)phenyl)(prop-2-yn-1-yl)amino)methyl)-2-methylquinazolin-4(3H)-one (CAS 152503-91-8), molecular formula C27H22N4O3S and molecular weight 482.55 g/mol, is a CATO reference standard with documented purity and traceability.

6-(((4-((1H-Indol-1-yl)sulfonyl)phenyl)(prop-2-yn-1-yl)amino)methyl)-2-methylquinazolin-4(3H)-one (C27H22N4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-(((4-((1H-Indol-1-yl)sulfonyl)phenyl)(prop-2-yn-1-yl)amino)methyl)-2-methylquinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC27H22N4O3S
Molecular Weight482.55 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)19.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2000
Nitrogen Atoms4
Sulfur Atoms1

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