5-methanesulfonylthiophene-3-carboxylic acid CAS 152538-40-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-methanesulfonylthiophene-3-carboxylic acid.

5-methanesulfonylthiophene-3-carboxylic acid (CAS 152538-40-4), molecular formula C6H6O4S2 and molecular weight 206.24 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 5-methanesulfonylthiophene-3-carboxylic acid (C6H6O4S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 206.24 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-methanesulfonylthiophene-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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