Salbutamol Impurity 145 CAS 152880-92-7
| CAS No. | 152880-92-7 |
| Molecular Formula | C9H8O4 |
| Molecular Weight | 180.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Salbutamol Impurity 145.
CATO supplies Salbutamol Impurity 145 (CAS 152880-92-7), a pharmacopoeial impurity reference standard (molecular formula C9H8O4, MW 180.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Salbutamol Impurity 145 (C9H8O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8O4 |
| Molecular Weight | 180.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
Related Salbutamol Standards
- Salbutamol Impurity 144 (CAS CATO-C4X-1176144)
- Salbutamol Impurity 152 (CAS CATO-C4X-1176152)
- Salbutamol Related Compound 4 (CAS 30186-16-4)
- Salbutamol Impurity 83 (CAS CATO-C4X-117683)
- Salbutamol Impurity 52 (CAS 26945-93-7)
- Salbutamol Impurity 89 (CAS CATO-C4X-117689)
- Salbutamol Impurity 93 (CAS 141024-79-5)
- Salbutamol Impurity 154 (CAS 82885-62-9)
Recommended Standards
- 2-Formylphenoxyacetic acid (CAS 6280-80-4)
- Ramosetron Impurity 22 (CAS CATO-C4X-118222)
- Valproate Impurity 71 (CAS CATO-C4X-116671)
- Acetaminophen Impurity 34 (CAS 146897-60-1)
- Posaconazole Impurity 167 (CAS CATO-C4X-1208167)
- Pioglitazone impurity 47 (CAS 146062-48-8)
- Atrasentan Impurity 125 (CAS 1063835-91-5)
- Pimitespib, >98% (HPLC) (CAS 1260533-36-5)
- (((1-(Bromomethyl)-3-methylcyclohexyl)oxy)methyl)benzene (CAS 1409639-90-2)
- Pregnenolone Impurity 4 (CAS 38372-24-6)
- 1,20-Dibromoeicosane (CAS 14296-16-3)
- 3-Bromo-5-(methoxymethyl)benzoic acid (CAS 1536144-89-4)
- 5-bromo-3-nitro-1H-indazole (CAS 921609-47-4)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com