(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodobenzylamino)-9H-purin-9-yl]-N-methyltetrahydrofuran-2-carboxamide CAS 152918-18-8

Purity 97%+In StockPharmaceutical Standards
CAS No.152918-18-8
Molecular FormulaC18H19IN6O4
Molecular Weight510.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodobenzylamino)-9H-purin-9-yl]-N-methyltetrahydrofuran-2-carboxamide CAS 152918-18-8 chemical structure

Description

The occurrence of (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodobenzylamino)-9H-purin-9-yl]-N-methyltetrahydrofuran-2-carboxamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodobenzylamino)-9H-purin-9-yl]-N-methyltetrahydrofuran-2-carboxamide (CAS 152918-18-8), molecular formula C18H19IN6O4 and molecular weight 510.29 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodobenzylamino)-9H-purin-9-yl]-N-methyltetrahydrofuran-2-carboxamide (C18H19IN6O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodobenzylamino)-9H-purin-9-yl]-N-methyltetrahydrofuran-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H19IN6O4
Molecular Weight510.29 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2000
Halogen ContentI-containing
Nitrogen Atoms6

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