3-FLuoro-5-(2,2,2-trifluoroethoxy)nitrobenzene CAS 1529357-37-6
| CAS No. | 1529357-37-6 |
| Molecular Formula | C8H5F4NO3 |
| Molecular Weight | 239.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-FLuoro-5-(2,2,2-trifluoroethoxy)nitrobenzene.
3-FLuoro-5-(2,2,2-trifluoroethoxy)nitrobenzene (CAS 1529357-37-6), molecular formula C8H5F4NO3 and molecular weight 239.12 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-FLuoro-5-(2,2,2-trifluoroethoxy)nitrobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 239.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-FLuoro-5-(2,2,2-trifluoroethoxy)nitrobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F4NO3 |
| Molecular Weight | 239.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related FLuoro Standards
- 4-Fluoro-1-nitro-2-(2,2,2-trifluoroethoxy)benzene (CAS 186386-91-4)
- 1-Fluoro-4-nitro-2-(2,2,2-trifluoroethoxy)benzene (CAS 1881328-94-4)
- 2-Fluoro-4-methoxy-3-nitro-1-(trifluoromethyl)benzene (CAS 1881329-69-6)
- (2-Fluoro-5-nitro-3-(trifluoromethyl)phenyl)methanol (CAS 2383806-14-0)
- 1-fluoro-2-methoxy-4-nitro-5-(trifluoromethyl)benzene (CAS 863983-95-3)
- 2-Fluoro-4-nitro-1-(2,2,2-trifluoroethoxy)benzene (CAS 956015-52-4)
- 4-Fluoro-2-nitro-1-(2,2,2-trifluoroethoxy)benzene (CAS 334929-98-5)
- 3-Fluoro-5-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 916212-03-8)
Recommended Standards
- N*1*-(2-Chloro-thiazol-5-ylmethyl)-N*1*-isopropyl-ethane-1,2-diamine (CAS 1353980-05-8)
- 2-Amino-5,5,5-trifluoro-4-(trifluoromethyl)pentanoic acid (CAS 16063-98-2)
- (4-(Chloromethyl)phenyl)methanesulfonyl Chloride (CAS 1314928-78-3)
- 1-Chloro-4-((2-chloroethyl)sulfonyl)benzene (CAS 16191-84-7)
- (3-Phenylimidazo[1,5-a]pyridin-1-yl)methanol (CAS 446830-56-4)
- 4-Methoxyphenol-2,3,5,6-d4 (CAS 159839-23-3)
- 1-(5-Fluoropyridin-3-yl)ethanone hydrobromide (CAS 1203710-42-2)
- Iron(III) phthalocyanine-4,4',4'',4'''-tetrasulfonic acid monosodium salt (CAS 944538-19-6)
- 3-Methoxy-4-[[4-(trifluoromethyl)phenyl]amino]cyclobut-3-ene-1,2-dione (CAS 1132827-67-8)
- 2-Chloro-5-(trifluoromethyl)phenylhydrazine (CAS 1869-22-3)
- 2-Bromo-4-(trifluoromethyl)aniline hydrochloride (CAS 54403-97-3)
- 3-Hydroxycyclohexanecarboxylic Acid (cis- and trans- mixture) (CAS 606488-94-2)
- 1-(3-Methoxy-4-nitrophenyl)pyrrolidine (CAS 339234-68-3)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com