Methyl 3-chloro-4-fluoro-5-nitrobenzoate CAS 1529446-36-3
| CAS No. | 1529446-36-3 |
| Molecular Formula | C8H5ClFNO4 |
| Molecular Weight | 233.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Methyl 3-chloro-4-fluoro-5-nitrobenzoate (CAS 1529446-36-3), a certified reference material (molecular formula C8H5ClFNO4, MW 233.58 g/mol) for analytical method development and quality control.
Methyl 3-chloro-4-fluoro-5-nitrobenzoate (C8H5ClFNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClFNO4 |
| Molecular Weight | 233.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 4-Chloro-2-fluoro-5-nitro-benzoic acid methyl ester (CAS 1070893-15-0)
- 4-Chloro-5-fluoro-2-nitrobenzoic Acid Methyl Ester (CAS 1113049-81-2)
- Methyl 2-chloro-3-fluoro-5-nitrobenzoate (CAS 1256260-39-5)
- 4-chloro-7-(trifluoromethyl)pyrido[3,2-d]pyrimidine (CAS 1256834-22-6)
- Methyl 3-Chloro-2-fluoro-5-nitrobenzoate (CAS 1509132-39-1)
- 2-(4-chloro-5-fluoro-2-nitrophenyl)acetic acid (CAS 1565927-14-1)
- 4-Chloro-2-(trifluoromethyl)pyrido[3,4-d]pyrimidine (CAS 161334-00-5)
- 2-Chloro-4-Fluoro-3-Methyl-5-Nitrobenzoic Acid (CAS 173315-56-5)
Recommended Standards
- 3-Chloro-7-(trifluoromethyl)pyrido[2,3-b]pyrazine (CAS 1774892-71-5)
- Methyl 2-chloro-4-fluoro-3-nitrobenzoate (CAS 1812892-64-0)
- Tris(trimethylsilyl)amine (CAS 1586-73-8)
- Methyl 2-chloro-3-fluoro-6-nitrobenzoate (CAS 1820739-83-0)
- N-(4-Chlorophenyl) 2-bromobenzamide (CAS 66569-06-0)
- 3-Methoxy-2-(trifluoromethyl)benzonitrile (CAS 1214385-02-0)
- 2-[[2-Chloro-5-(Trifluoromethyl)Phenyl]Amino]Benzoic Acid (CAS 102583-95-9)
- N1-methyl-n1-(2-methyl-4,5,6,7-tetrahydro-2h-indazol-3-yl)-2-chloroacetamide (CAS 246020-77-9)
- 1-(2-(2-Chloro-6H-indolo[2,3-b]quinoxalin-6-yl)acetyl)-3-methyl-4-(1-phenylethylidene)-1H-pyrazol-5(4H)-one (CAS 119457-18-0)
- 1,1'-(5-Hydroxypyridine-3,4-diyl)bis(ethan-1-one) (CAS 1393557-13-5)
- 1-(2-Chlorobenzyl)urea (CAS 4654-63-1)
- 3-Bromo-4-fluoroaniline (CAS 656-64-4)
- 5-(4-Chlorobenzoyl)-N2-(4-chlorophenyl)-1,3-thiazole-2,4-diamine (CAS 107401-72-9)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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