3-(3,5-Difluorophenyl)chroman-4-one CAS 1529771-72-9
| CAS No. | 1529771-72-9 |
| Molecular Formula | C15H10F2O2 |
| Molecular Weight | 260.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(3,5-Difluorophenyl)chroman-4-one (C15H10F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-(3,5-Difluorophenyl)chroman-4-one (CAS 1529771-72-9), molecular formula C15H10F2O2 and molecular weight 260.24 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(3,5-Difluorophenyl)chroman-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10F2O2 |
| Molecular Weight | 260.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Difluorophenyl Standards
- 3-(2,4-Difluorophenyl)-N-methylimidazo[1,2-a]pyrazin-8-amine (CAS 787590-95-8)
- 3-(3,4-Difluorophenyl)-N-methylimidazo[1,2-a]pyrazin-8-amine (CAS 787591-11-1)
- 2-(2,6-Difluorophenyl)-1,2,3,4-tetrahydroquinolin-4-amine (CAS 1923082-46-5)
- 1-(2,4-Difluorophenyl)-3-(m-tolyl)propan-1-one (CAS 898768-16-6)
- 1-(3,4-Difluorophenyl)-3-(m-tolyl)propan-1-one (CAS 898768-18-8)
- 1-(3,4-Difluorophenyl)-3-(o-tolyl)propan-1-one (CAS 898790-11-9)
- 1-(3,4-Difluorophenyl)-3-(p-tolyl)propan-1-one (CAS 898769-37-4)
- 1-(3,5-Difluorophenyl)-3-(o-tolyl)propan-1-one (CAS 898790-14-2)
Recommended Standards
- Sodium 6-methoxynaphthalene-2-sulfonate (CAS 149353-39-9)
- 2-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone (CAS 15485-65-1)
- 1,3-Bis(4-fluorophenyl)propane-1,3-dione (CAS 1493-51-2)
- 6-Methyluridine (CAS 16710-13-7)
- 2-Hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)propanoic acid (CAS 1488807-49-3)
- 2-azido-1-(4-chlorophenyl)ethan-1-one (CAS 26086-60-2)
- 14-Acetylvirescenine (CAS 71609-79-5)
- 3'-O-Ac-dTTP (CAS 90290-82-7)
- 2-Chloro-3-(dimethoxymethyl)-4-((trimethylsilyl)ethynyl)pyridine (CAS 1171920-13-0)
- 4-(2-Phenyldiazenyl)-N-2-propyn-1-ylbenzamide (CAS 1314406-80-8)
- 3-Methylene Piperidine Hydrochloride (CAS 155137-12-5)
- methyl 2-methylpent-4-ynoate (CAS 1481509-00-5)
- Lubiprostone Impurity 33 (CAS CATO-C4X-113633)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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