2-Bromo-6-fluoro-3-methoxybenzoic acid CAS 1532387-46-4
| CAS No. | 1532387-46-4 |
| Molecular Formula | C8H6BrFO3 |
| Molecular Weight | 249.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 249.03 g/mol gives 2-Bromo-6-fluoro-3-methoxybenzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Bromo-6-fluoro-3-methoxybenzoic acid (CAS 1532387-46-4) is a high-purity analytical reference standard with the molecular formula C8H6BrFO3 and a molecular weight of 249.03 g/mol.
The molecular framework of 2-Bromo-6-fluoro-3-methoxybenzoic acid (C8H6BrFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-6-fluoro-3-methoxybenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO3 |
| Molecular Weight | 249.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
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Recommended Standards
- 1-Bromo-3-ethynyl-5-(trifluoromethyl)benzene (CAS 1494947-64-6)
- 2-(4-Hydroxyphenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione (CAS 1613586-40-5)
- 4-Bromo-2-fluoro-6-methoxybenzoic Acid (CAS 1472104-49-6)
- 4-Bromo-2-fluoro-5-methoxybenzoic acid (CAS 1620677-51-1)
- Butyl 4-[(chloroacetyl)amino]benzoate (CAS 106214-24-8)
- 1246172-77-9 2-Amino-1-(4-methyl-1-piperidinyl)-3-phenyl-1-propanone hydrochloride 3102AD C15H23ClN2O (CAS 1246172-77-9)
- Methyl 4-hydroxypicolinate Hydrochloride (CAS 1256633-27-8)
- 1-Fluoro-2-iodo-4-(trifluoromethyl)benzene (CAS 110192-48-8)
- 2-Methyl-6-propylpiperidine (CAS 68170-79-6)
- Butyl 5,8-dimethyl-4-morpholinoquinoline-2-carboxylate (CAS 887589-64-2)
- 1-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopentane-1-carboxylic acid (CAS 2227245-84-1)
- 7-Bromo-[1,2,3]triazolo[1,5-a]pyridine (CAS 107465-26-9)
- 2-Amino-5-chloro-N-(o-tolyl)benzamide (CAS 4145-15-7)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
Why CATO?
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