trans-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic acid CAS 153259-69-9
| CAS No. | 153259-69-9 |
| Molecular Formula | C20H25NO4 |
| Molecular Weight | 343.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of trans-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic acid (C20H25NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies trans-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic acid (CAS 153259-69-9), a certified reference material (molecular formula C20H25NO4, MW 343.42 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), trans-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H25NO4 |
| Molecular Weight | 343.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 1 |
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- 5'-Cyano-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid (CAS 1159596-08-3)
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Recommended Standards
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- 5-(Difluoromethyl)pyridin-3-ol (CAS 1393541-20-2)
- 2-(4-Chlorophenyl)-6-phenyl-4-(trifluoromethyl)nicotinonitrile (CAS 214545-97-8)
- Methyl 2-(6-ethyl-4-oxoquinolin-1(4H)-yl)acetate (CAS 1279218-40-4)
- 2-Bromo-N-(4-isopropylphenyl)acetamide (CAS 171241-77-3)
- 2-Methyl-8-(2,2,2-trifluoroethyl)quinoxaline (CAS 1416821-81-2)
- N-(1,2,2-Trichlorovinyl)-N'-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea (CAS 646989-55-1)
- 2-Propenoic acid, polymer with ethyl 2-propenoate and N-(hydroxymethyl)-2-propenamide (CAS 25852-42-0)
- Diosmin Impurity 16 (CAS CATO-C4X-115616)
- 4-Bromo-2-(1-methylethyl)benzenemethanol (CAS 1370600-49-9)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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