2-Chloro-6-fluorobenzo[d]oxazole CAS 153403-53-3
| CAS No. | 153403-53-3 |
| Molecular Formula | C7H3ClFNO |
| Molecular Weight | 171.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-6-fluorobenzo[d]oxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-6-fluorobenzo[d]oxazole (CAS 153403-53-3), molecular formula C7H3ClFNO and molecular weight 171.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-6-fluorobenzo[d]oxazole (C7H3ClFNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClFNO |
| Molecular Weight | 171.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine (CAS 1020253-21-7)
- 2-Chloro-4-fluorobenzoxazole (CAS 1163123-39-4)
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- 3-Chloro-7-fluorobenzo[d]isoxazole (CAS 1352899-19-4)
Recommended Standards
- 2-Chloro-7-fluorobenzoxazole (CAS 153403-52-2)
- 5-Chloro-6-fluoropyrazolo[1,5-a]pyrimidine (CAS 1610021-36-7)
- 2-Chloro-7-fluoro-5H-pyrrolo[2,3-b]pyrazine (CAS 1392803-74-5)
- 5-Chloro-4-fluoro-2-hydroxybenzonitrile (CAS 1691192-63-8)
- (S)-3-Aminopentanoicacid (CAS 14389-77-6)
- 1-Butylimidazole (CAS 4316-42-1)
- Acetochlor-2-hydroxy (CAS 60090-47-3)
- Methyl 3-formylbenzo[d]pyrrolo[2,1-b]thiazole-1-carboxylate (CAS 136427-69-5)
- Saxagliptin Imine Impurity (CAS 1350800-76-8)
- 1-(2-Hydroxyethyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 926250-42-2)
- 2-(3-((tert-Butoxycarbonyl)amino)propoxy)ethyl 4-methylbenzenesulfonate (CAS 912849-70-8)
- Ethyl 5-amino-1-(naphthalen-2-yl)-1H-pyrazole-4-carboxylate (CAS 304683-30-5)
- Cycloheptanol (CAS 502-41-0)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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