Fexofenadine Hydrochloride CAS 153439-40-8
| CAS No. | 153439-40-8 |
| Molecular Formula | C32H39NO4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Fexofenadine Hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 538.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Fexofenadine Hydrochloride (CAS 153439-40-8) is a high-purity analytical reference standard with the molecular formula C32H39NO4HCl and a molecular weight of 538.12 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H39NO4 HCl |
| Molecular Weight | 538.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Fexofenadine Standards
- Fexofenadine Impurity 13 (CAS 1010812-98-2)
- Fexofenadine EP Impurity E (CAS 115-46-8)
- Fexofenadine EP Impurity G (CAS 1187954-57-9)
- Fexofenadine Impurity 23 (CAS 1208313-13-6)
- Fexofenadine-d10 HCl (CAS 1215821-44-5)
- Fexofenadine-d6 Methyl Ester (CAS 1286458-00-1)
- Fexofenadine Impurity 11 (CAS 1347311-10-7)
- Fexofenadine Impurity 40 (CAS 1390644-37-7)
Recommended Standards
- 2-(Difluoromethyl)-4-fluoro-6-hydroxypyridine-3-acetonitrile (CAS 1806848-98-5)
- 4-(3-methoxycarbonyl-2H-chromen-6-yl)but-3-ynoic acid (CAS 2550903-41-6)
- tert-Butyl 4-cyano-4-(m-tolyl)piperidine-1-carboxylate (CAS 1823241-26-4)
- 1-Propyl-3-(3-pyridin-3-yl-benzyl)-piperazin-2-one (CAS 1361111-51-4)
- L-erythro-4-Fluoroisoglutamine (CAS 374560-28-8)
- 5-(Prop-2-yn-1-ylthio)-1,3,4-thiadiazole-2(3H)-thione (CAS 53918-17-5)
- 2,4-Difluoro-1-(2,2,2-trifluoroethyl)benzene (CAS 1092350-12-3)
- 2,2-Dimethyl-1-(3-methyl-1H-pyrazol-1-yl)propan-1-one (CAS 89444-90-6)
- 3-(2-Chloroacetyl)-1-cyclopentylurea (CAS 565169-46-2)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
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