Folic Acid NHS Ester (gamma : alpha =2 :1) CAS 153445-05-7
| CAS No. | 153445-05-7 |
| Molecular Formula | C23H22N8O8 |
| Molecular Weight | 538.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Folic Acid NHS Ester (gamma : alpha =2 :1) (CAS 153445-05-7), a certified reference material (molecular formula C23H22N8O8, MW 538.47 g/mol) for analytical method development and quality control.
Folic Acid NHS Ester (gamma : alpha =2 :1) (C23H22N8O8) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H22N8O8 |
| Molecular Weight | 538.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 8 |
Related Folic Standards
- Folic Acid Impurity 71 (CAS CATO-C4X-139571)
- Folic Acid Impurity 46 Disodium Salt (CAS 914800-65-0)
- Folic Acid Impurity 63 (CAS CATO-C4X-139563)
- Folic Acid Impurity 35 (CAS 33157-07-2)
- Folic Acid-D5 N-Nitroso (CAS CATO-C4X-139568)
- Folic Acid Impurity 56 (CAS CATO-C4X-139556)
- Folic Acid Impurity N2 (CAS 2800-34-2)
- Folic Acid Impurity 16 (CAS 68538-85-2)
Recommended Standards
- Fosaprepitant Impurity 38 (CAS 990-91-0)
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- Latamoxef impurity 41 (CAS CATO-C4X-179841)
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