3-(8-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxypropanenitrile CAS 1538190-06-5
| CAS No. | 1538190-06-5 |
| Molecular Formula | C11H10BrNO3 |
| Molecular Weight | 284.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 284.11 g/mol gives 3-(8-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxypropanenitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(8-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxypropanenitrile (CAS 1538190-06-5), molecular formula C11H10BrNO3 and molecular weight 284.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 3-(8-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxypropanenitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(8-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxypropanenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10BrNO3 |
| Molecular Weight | 284.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-4-nitro-6-isopropyl (1H)Indazole (CAS 1000340-89-5)
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- 6-Bromo-1-(2-methoxyethyl)-2,3-dihydro-1h-indole-2,3-dione (CAS 1020994-26-6)
- 4-Bromo-7-ethoxy-1H-indole-2-carboxylic acid (CAS 1098340-08-9)
- 8-Bromo-5-hydroxy-4-(2-hydroxyethyl)quinolin-2-one (CAS 1155270-69-1)
- 7-Bromo-N-ethoxybenzofuran-2-carboxamide (CAS 1208690-20-3)
- Methyl 2-(6-bromo-5-methyl-3H-imidazo[4,5-b]pyridin-2-yl)acetate (CAS 1211507-06-0)
- 4-Bromo-6,7-dimethoxyisoquinolin-1(2H)-one (CAS 1211580-83-4)
Recommended Standards
- 5-Bromo-3-hydroxy-1H-indole-2-carboxylic acid ethyl ester (CAS 153501-30-5)
- 1-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol (CAS 1586045-19-3)
- Ethyl 4-bromo-3-hydroxy-1H-indole-2-carboxylate (CAS 153501-22-5)
- 3-Bromo-5,7-dimethoxyquinolin-4(1H)-one (CAS 1592407-70-9)
- 3-((Nitrooxy)methyl)phenyl isonicotinate (CAS 2444010-45-9)
- 2-(1-(4-Aminobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl)acetic acid (CAS 1374408-23-7)
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate (CAS 194474-73-2)
- 4-(1-Bromoethyl)-9-chloroacridine (CAS 55816-91-6)
- 2-(4,6-Diphenyl-1,3,5-triazin-2-yl)phenol (CAS 3202-86-6)
- Lifitegrast Impurity 15 (CAS 2295862-00-7)
- 2-(3-Methyl-1h-pyrazol-1-yl)benzoic acid hydrochloride (CAS 1864015-05-3)
- 2-(Bromomethyl)benzo[d]oxazole-5-carboxaldehyde (CAS 1806426-78-7)
- 1-(3-Ethynylbenzyl)-4-methylpiperazine (CAS 1421580-62-2)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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