Biapenem Impurity 21 CAS 153851-71-9
| CAS No. | 153851-71-9 |
| Molecular Formula | C5H8N3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Biapenem Impurity 21.
Biapenem Impurity 21 (CAS 153851-71-9) is a certified pharmaceutical impurity reference standard with the molecular formula C5H8N3SCl and a molecular weight of 177.65 g/mol.
Based on its molecular formula C5H8N3SCl, Biapenem Impurity 21 contains a nitrile group, sulfur-containing functionality, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 177.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H8N3S Cl |
| Molecular Weight | 177.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Biapenem Standards
- Biapenem Impurity 20 (CAS 106-95-6)
- Biapenem impurity 35 (CAS 1080648-58-3)
- Biapenem (CAS 120410-24-4)
- Biapenem-13C2,15N3 (CAS 120410-24-4 (unlabeled))
- Biapenem impurity 33 (CAS 155835-09-9)
- Biapenem impurity 1 (CAS CATO-C4X-22731)
- Biapenem impurity 11 (CAS CATO-C4X-227311)
- Biapenem impurity 12 (CAS CATO-C4X-227312)
Recommended Standards
- Fulvestrant Impurity 15 (CAS 38649-18-2)
- Indapamide Impurity 22 (CAS 6872-06-6)
- Atenolol EP Impurity G(Sodium Salt) (CAS CATO-C4X-154911)
- 4-[5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl]piperidine (CAS 493024-40-1)
- 1H,4H,5H,7H-pyrano[3,4-b]pyrrol-4-one (CAS 1369248-13-4)
- 2-(Chloromethyl)-4,6-dihydroxybenzaldehyde (CAS 378749-91-8)
- 4-(1H-Indol-3-yl)butanoyl chloride (CAS 1548278-74-5)
- 4'-(tert-Butyl)-[1,1'-biphenyl]-2-carbonitrile (CAS 192699-49-3)
- tert-Butyl 4-(2-hydroxypropan-2-yl)piperidine-1-carboxylate (CAS 1935325-64-6)
- Peptide Impurity 27 (CAS 1350456-68-6)
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