(5R,6R)-5-Fluoro-6-isopropyldihydropyrimidine-2,4(1H,3H)-dione CAS 154121-09-2
| CAS No. | 154121-09-2 |
| Molecular Formula | C7H11FN2O2 |
| Molecular Weight | 174.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies (5R,6R)-5-Fluoro-6-isopropyldihydropyrimidine-2,4(1H,3H)-dione (CAS 154121-09-2), a certified reference material (molecular formula C7H11FN2O2, MW 174.17 g/mol) for analytical method development and quality control.
(5R,6R)-5-Fluoro-6-isopropyldihydropyrimidine-2,4(1H,3H)-dione (C7H11FN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H11FN2O2 |
| Molecular Weight | 174.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-Fluoro-6-phenylpyridazine (CAS 144864-03-9)
- methyl rel-(1R,2R,4S)-2-fluoro-7-oxabicyclo[2.2.1]heptane-2-carboxylate (CAS 1624052-26-1)
- 1-Fluoro-2-naphthaldehyde (CAS 143901-96-6)
- 1706439-17-9 AS-46635 ethyl cis-3-(-2-fluorocyclopropyl)-3-oxopropanoate (CAS 1706439-17-9)
- (2-Amino-5-phenylthiophene-3-carbonyl)glycine (CAS 446831-10-3)
- [1,1'-Biphenyl]-4-yl cyclobutanecarboxylate (CAS 667886-12-6)
- Heptachlor epoxide Impurity 4 (CAS 76986-14-6)
- 2-(4-(Diethylamino)thiophen-2-yl)ethyl pyrimidine-5-carboxylate (CAS 823792-77-4)
- (2-(Trifluoromethyl)quinolin-6-yl)methanamine (CAS 1260667-11-5)
- 2-(4-Acetylphenoxy)-N-(3,5-dimethoxyphenyl)acetamide (CAS 565165-48-2)
- rac-(5R,6R)-7-methyl-8-oxo-6-phenyl-7-azaspiro[3.5]nonane-5-carboxylic acid (CAS 1969288-37-6)
- 4-(3,5-Dimethoxyphenyl)butan-1-amine (CAS 1480770-86-2)
- 4-Chloro-1h-pyrazole-3-carbonyl chloride (CAS 717871-75-5)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
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