(3E)-3-[Amino(4-methylpiperazin-1-yl)methylidene]prop-1-ene-1,1,3-tricarbonitrile CAS 154124-60-4
| CAS No. | 154124-60-4 |
| Molecular Formula | C12H14N6 |
| Molecular Weight | 242.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 242.28 g/mol gives (3E)-3-[Amino(4-methylpiperazin-1-yl)methylidene]prop-1-ene-1,1,3-tricarbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (3E)-3-[Amino(4-methylpiperazin-1-yl)methylidene]prop-1-ene-1,1,3-tricarbonitrile (CAS 154124-60-4), a certified reference material (molecular formula C12H14N6, MW 242.28 g/mol) for analytical method development and quality control.
The molecular framework of (3E)-3-[Amino(4-methylpiperazin-1-yl)methylidene]prop-1-ene-1,1,3-tricarbonitrile (C12H14N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3E)-3-[Amino(4-methylpiperazin-1-yl)methylidene]prop-1-ene-1,1,3-tricarbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14N6 |
| Molecular Weight | 242.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 6 |
Related E Standards
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- 8-amino-5-ethyl-3-methyl-3H,4H,5H-pyrazolo[3,4-c]quinolin-4-one (CAS 1189306-45-3)
- 1-(4-((2-Amino-6-methylpyrimidin-4-yl)amino)phenyl)ethanone (CAS 131554-47-7)
- 1-(4-((6-Amino-2-methylpyrimidin-4-yl)amino)phenyl)ethanone (CAS 144174-16-3)
- 2-Amino-6-(4-methylpiperazin-1-yl)pyridine-3,5-dicarbonitrile (CAS 154124-65-9)
- 5-Amino-1-(4-ethoxyphenyl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 1962540-59-5)
- 2-Amino-N-benzyl-4-methylpyrimidine-5-carboxamide (CAS 400074-74-0)
Recommended Standards
- 1-Cyclohexyl-4-methyl-2-(trifluoromethyl)benzene (CAS 1449293-48-4)
- (3S)-1-(2-Aminopyridin-4-yl)-3-cyclopropyl-2-oxopyrrolidine-3-carbonitrile (CAS 1649463-89-7)
- N-(2-(Dimethylamino)pyrimidin-5-yl)benzamide (CAS 1396795-01-9)
- 3-(Pyridin-3-ylmethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one (CAS 1713639-41-8)
- 2-Bromo-6-(difluoromethyl)-4-(trifluoromethyl)pyridine (CAS 1806770-83-1)
- 5-cyano-N,N-dimethylpyridine-2-carboxamide (CAS 1343225-44-4)
- Ammonium nitrate, 5% (CAS 6484-52-2)
- 2,3-Dimethoxybenzamide (CAS 1521-39-7)
- 8-Methoxyquinoline 1-oxide (CAS 22614-90-0)
- (4-(Benzyloxy)-3-chloro-5-methoxyphenyl)boronic acid (CAS 1218790-59-0)
- 2-Methoxy-5-(trifluoromethyl)pyrimidine (CAS 176214-14-5)
- (E)-N-(5-(3-(dimethylamino)acryloyl)-4-methylthiazol-2-yl)-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 1211991-26-2)
- N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 297150-41-5)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
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