4-(3-Bromophenoxy)-2-chloro-5-fluoropyrimidine CAS 1542833-32-8
| CAS No. | 1542833-32-8 |
| Molecular Formula | C10H5BrClFN2O |
| Molecular Weight | 303.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3-Bromophenoxy)-2-chloro-5-fluoropyrimidine (CAS 1542833-32-8), molecular formula C10H5BrClFN2O and molecular weight 303.51 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, 4-(3-Bromophenoxy)-2-chloro-5-fluoropyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 303.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H5BrClFN2O |
| Molecular Weight | 303.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromophenoxy Standards
- 4-(4-Bromophenoxy)-2-chloro-5-fluoropyrimidine (CAS 1500257-47-5)
- 4-(2-Bromophenoxy)-2-chloro-5-fluoropyrimidine (CAS 1503988-07-5)
- 2-(4-Bromophenoxy)-5-chloro-3-fluoropyridine (CAS 1539642-62-0)
- 2-(4-Bromophenoxy)-N-(3-hydroxypropyl)propanamide (CAS 1156804-06-6)
- 3-(2-(3-Bromophenoxy)acetamido)propanoic acid (CAS 1099157-03-5)
- 3-(2-(4-Bromophenoxy)acetamido)propanoic acid (CAS 446828-74-6)
- 4-(4-Bromophenoxy)-1-methyl-1h-pyrazolo[3,4-d]pyrimidine (CAS 5417-91-4)
- 4-(4-Bromophenoxy)tetrahydro-2H-thiopyran 1,1-dioxide (CAS 2001951-51-3)
Recommended Standards
- 6-Bromo-4-chloro-7-fluoroquinoline-3-carboxamide (CAS 1821429-67-7)
- 5-(2-Bromo-4-fluorophenoxy)-4-chloropyrimidine (CAS 2169919-47-3)
- Methyl 2-chloro-5-iodothiazole-4-carboxylate (CAS 1235034-78-2)
- 7-((tert-butyldimethylsilyl)oxy)-N-methoxy-N-methylheptanamide (CAS 2007908-84-9)
- Methyl 2-methylbutanimidate (CAS 1248269-53-5)
- 1-((5-Bromo-3-methylpentyl)oxy)octane (CAS 1490114-92-5)
- 2-Ethyl-6-methylphenyl isocyanate (CAS 75746-71-3)
- 1-(3-Cyano-5-(ethoxycarbonyl)-6-methylpyridin-2-yl)piperidine-4-carboxylic acid (CAS 919354-24-8)
- (S)-2-isobutyramido-4-methylpentanoic acid (CAS 55443-75-9)
- Methyl (2S)-2-[bis[(2-methylpropan-2-yl)oxycarbonyl]amino]-5-hydroxypentanoate (CAS 367968-06-7)
- Copper(II) Dimethyldithiocarbamate (CAS 137-29-1)
- Octahydropyrrolo[3,4-b]pyrrole dihydrochloride (CAS 479070-13-8)
- 7-Bromo-2,4a,9,9a-tetrahydro-1H-pyrido[3,4-b]indol-1-one (CAS 1892784-13-2)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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