4-Chloro-8-methoxyquinazoline CAS 154288-09-2
| CAS No. | 154288-09-2 |
| Molecular Formula | C9H7ClN2O |
| Molecular Weight | 194.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 194.62 g/mol gives 4-Chloro-8-methoxyquinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Chloro-8-methoxyquinazoline (CAS 154288-09-2), a certified reference material (molecular formula C9H7ClN2O, MW 194.62 g/mol) for analytical method development and quality control.
4-Chloro-8-methoxyquinazoline (C9H7ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-8-methoxyquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClN2O |
| Molecular Weight | 194.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-6-methyl-7H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS 1000340-13-5)
- 4-Chloro-7-methyl-1H-indazole-3-carbaldehyde (CAS 1000340-67-9)
- 6-(4-Chloro-1H-pyrazol-1-yl)pyridin-3-amine (CAS 1006961-40-5)
- 4-Chloro-1-methyl-1,8-naphthyridin-2(1H)-one (CAS 1009360-86-4)
- 4-Chloro-6-(4-methylpyrazol-1-yl)pyrimidine (CAS 1015845-71-2)
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- 2-Chloro-5-(4H-1,2,4-triazol-4-yl)aniline (CAS 1017791-27-3)
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Recommended Standards
- 4-Chloro-1-(pyridin-2-yl)-1H-pyrazol-5-amine (CAS 1506612-64-1)
- 4-Chloro-2-methylquinazolin-8-ol (CAS 154288-10-5)
- 2-Chloro-4-(1-methyl-1h-pyrazol-5-yl)pyrimidine (CAS 1503746-05-1)
- 1-(6-Chloro-1H-indazol-3-yl)ethanone (CAS 1547036-10-1)
- (S)-2-Amino-2-(3-bromo-4-chlorophenyl)ethanol (CAS 1272734-29-8)
- 5-Hydrazino-1-phenyl-1H-1,2,3,4-tetraazole (CAS 5533-43-7)
- 4,4'-(9,9-Diethyl-9H-fluorene-2,7-diyl)dibenzaldehyde (CAS 2116542-14-2)
- 6-(3,4-Dimethylphenyl)-3-(pyrrolidin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706437-66-2)
- Ofloxacin Impurity 48 (CAS 126911-77-1)
- N-(1,1-dioxo-1λ⁶-thietan-3-yl)-1-(hydrazinecarbonyl)formamide (CAS 1856309-61-9)
- 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethoxy)phenol (CAS 1689502-03-1)
- 4-methoxy-3-(1H-1,2,3,4-tetrazol-1-yl)aniline (CAS 891017-36-0)
- 3-(1-Methyl-1h-1,2,4-triazol-5-yl)propan-1-ol (CAS 1468804-53-6)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
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