3-(1H-Indol-2-yl)-1-methylpyridin-1-ium iodide CAS 15432-27-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(1H-Indol-2-yl)-1-methylpyridin-1-ium iodide.

3-(1H-Indol-2-yl)-1-methylpyridin-1-ium iodide (CAS 15432-27-6), molecular formula C14H13N2I and molecular weight 336.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(1H-Indol-2-yl)-1-methylpyridin-1-ium iodide (C14H13N2I) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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