4-(2,2-Difluoroethyl)thiomorpholine-3-carboxylic acid CAS 1543428-68-7
| CAS No. | 1543428-68-7 |
| Molecular Formula | C7H11F2NO2S |
| Molecular Weight | 211.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(2,2-Difluoroethyl)thiomorpholine-3-carboxylic acid (CAS 1543428-68-7), a certified reference material (molecular formula C7H11F2NO2S, MW 211.23 g/mol) for analytical method development and quality control.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(2,2-Difluoroethyl)thiomorpholine-3-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11F2NO2S |
| Molecular Weight | 211.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoroethyl Standards
- 1-(2,2-difluoroethyl)-1H-pyrazole-4-sulfonamide (CAS 1540633-86-0)
- 1-(2,2-difluoroethyl)-1,2,3,4-tetrahydroquinolin-5-amine (CAS 1179290-21-1)
- 1-(1,1-Difluoroethyl)-3-(trifluoromethyl)benzene (CAS 1071212-33-3)
- 1-(1,1-Difluoroethyl)-2-(trifluoromethyl)benzene (CAS 1138445-29-0)
- 1-(1,1-Difluoroethyl)-4-(trifluoromethyl)benzene (CAS 1138445-30-3)
- methyl 4-(2,2-difluoroethyl)morpholine-3-carboxylate (CAS 1564653-76-4)
- 2,2-Difluoroethyl Triflate (CAS 74427-22-8)
- n-(2,2-Difluoroethyl)-3-morpholinopropan-1-amine (CAS 1178130-12-5)
Recommended Standards
- 7-(4-Fluorophenyl)-1H-indole (CAS 153758-21-5)
- tert-Butyl 4-amino-3-fluorobenzoate (CAS 157665-53-7)
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- [(3Z)-2-Oxo-1-phenyl-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate (CAS 478261-18-6)
- 1-[4-(4-Hydroxybenzyl)phenoxy]-2-diethylaminoethane hydrochloride (CAS 116505-58-9)
- Ethyl 4-cyclopropyl-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 1191094-23-1)
- (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(((2R,3S,4R)-1,2,4-trihydroxy-5-oxopentan-3-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid (CAS 475598-94-8)
- Tizanidine Nitroso Impurity 13 (CAS CATO-C4X-144513)
- (1r)-1-(4-Bromothiophen-2-yl)-2,2,2-trifluoroethan-1-ol (CAS 1423015-71-7)
- 8,5'-(S)-Cycloadenosine (CAS 41432-67-1)
- 2-Chloro-7-methoxyquinoxaline (CAS 55686-93-6)
- 7-Bromo-1-propylindolin-2-one (CAS 1706432-65-6)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
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