2-[(4-fluorophenyl)methyl]-5-iodothiophene CAS 154355-88-1
| CAS No. | 154355-88-1 |
| Molecular Formula | C11H18FIS |
| Molecular Weight | 328.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[(4-fluorophenyl)methyl]-5-iodothiophene.
2-[(4-fluorophenyl)methyl]-5-iodothiophene (CAS 154355-88-1) is a high-purity analytical reference standard with the molecular formula C11H18FIS and a molecular weight of 328.23 g/mol.
Owing to sulfur-containing functionality, fluorine/iodine substitution, 2-[(4-fluorophenyl)methyl]-5-iodothiophene is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 328.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[(4-fluorophenyl)methyl]-5-iodothiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H18FIS |
| Molecular Weight | 328.23 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/I-containing |
| Sulfur Atoms | 1 |
Related fluorophenyl Standards
- 7-(4-Fluorophenyl)-7-oxoheptanoic acid (CAS 898788-13-1)
- N-(2-Fluorophenyl)-N'-[2-methoxy-5-(trifluoromethyl)phenyl]urea (CAS 917389-24-3)
- 2-(3-(4-Fluorophenyl)-6-oxopyridazin-1(6H)-yl)-N-(5-methylisoxazol-3-yl)acetamide (CAS 922860-81-9)
- 4-(2-Fluorophenyl)-5-methyl-2-(4-nitrobenzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860789-04-4)
- 4-(3-Fluorophenyl)-3-methyl-1-[(4-nitrophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860786-12-5)
- 4-(4-Fluorophenyl)-5-methyl-2-(4-nitrobenzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860651-09-8)
- 2-(4-(4-Fluorophenyl)piperazine-1-carbonyl)benzoic acid (CAS 697741-72-3)
- N-(4-Fluorophenyl)-2-((2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinolin-5-yl)oxy)acetamide (CAS 850904-69-7)
Recommended Standards
- 4-Bromo-2-methyl-5-((1-(5-methylthiophen-2-yl)ethyl)amino)pyridazin-3(2H)-one (CAS 1428049-98-2)
- 1-Iodo-4-(4-propyl-cyclohexyl)-benzene (CAS 860639-66-3)
- tert-Butyl 4-(3,5-dichlorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate (CAS 1415468-87-9)
- 3-{[3-(1,1,2,2-tetrafluoroethoxy)phenyl]amino}-2-(1H-1,2,3,4-tetrazol-5-yl)prop-2-enenitrile (CAS 946386-40-9)
- Ms-PEG5-t-butyl ester (CAS 870487-48-2)
- Ethyl 3-(1-methyl-1H-pyrazol-5-yl)-3-oxopropanoate (CAS 1356404-50-6)
- N,N-dimethyl-2-((tetrahydro-2H-thiopyran-4-yl)amino)acetamide (CAS 1153145-52-8)
- 1,6-Nonadien-3-ol, 3,7-dimethyl-, 3-acetate (CAS 61931-80-4)
- 7-Nitroindole-3-acetic Acid (CAS 1557-14-8)
- 4-Chloro-3,5-dimethoxybenzoic acid (CAS 56518-46-8)
- tert-Butyl 2-(4-bromophenyl)-3-thioxo-1,4,8-triazaspiro[4.5]dec-1-ene-8-carboxylate (CAS 1325306-86-2)
- 5-Hydroxybenzofuran-4-carbaldehyde (CAS 59254-30-7)
- 4-Chloro-n-cyclopropyl-3-iodobenzamide (CAS 882679-31-4)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
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