Rac-ethyl (2R)-1-(2,2-difluoroethyl)piperidine-2-carboxylate CAS 1543650-44-7
| CAS No. | 1543650-44-7 |
| Molecular Formula | C10H17F2NO2 |
| Molecular Weight | 221.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rac-ethyl (2R)-1-(2,2-difluoroethyl)piperidine-2-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Rac-ethyl (2R)-1-(2,2-difluoroethyl)piperidine-2-carboxylate (CAS 1543650-44-7), molecular formula C10H17F2NO2 and molecular weight 221.24 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Rac-ethyl (2R)-1-(2,2-difluoroethyl)piperidine-2-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 221.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17F2NO2 |
| Molecular Weight | 221.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-Amino-3-(pyridin-2-yl)isothiazole-5-carboxylic acid (CAS 1467671-48-2)
- 1-(4-Nitrophenyl)-1h-imidazole-2-thiol (CAS 155655-99-5)
- tert-Butyl (3R)-3-(difluoromethyl)pyrrolidine-1-carboxylate (CAS 1443983-90-1)
- 3-(4,4-Difluoropiperidin-1-yl)-2,2-dimethylpropionic acid (CAS 1889794-96-0)
- Dimethyl 5,6,7,8-tetrahydronaphthalene-2,3-dicarboxylate (CAS 51510-78-2)
- 14276-67-6 2,2-Dimethylpropane-1,3-diyl bis(3-oxobutanoate) 6986AA C13H20O6 (CAS 14276-67-6)
- n-(2-Chlorophenyl)-2-(n-hydroxyimino)acetamide (CAS 53629-64-4)
- 2-Methyl-4-(3-nitrophenyl)-1,3-thiazole (CAS 39541-91-8)
- (S)-N-Cyclopropyl-N-methylpiperidin-3-amine (CAS 1354019-45-6)
- 4-Decanoyl morpholine (CAS 5299-65-0)
- Terpin (CAS 565-48-0)
- (2-Methyl-4-(n-propylsulfamoyl)phenyl)boronic acid (CAS 1217501-47-7)
- Lesinurad Impurity 21 (CAS 1533519-84-4)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
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