Ethyl 2-iodonicotinate CAS 154366-01-5
| CAS No. | 154366-01-5 |
| Molecular Formula | C8H8INO2 |
| Molecular Weight | 277.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 277.06 g/mol gives Ethyl 2-iodonicotinate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-iodonicotinate (CAS 154366-01-5) is a high-purity analytical reference standard with the molecular formula C8H8INO2 and a molecular weight of 277.06 g/mol.
Structurally, Ethyl 2-iodonicotinate (C8H8INO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 277.06 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2-iodonicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8INO2 |
| Molecular Weight | 277.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
Recommended Standards
- (S)-3-iodo-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 1639901-75-9)
- Methyl 2-amino-6-iodobenzoate (CAS 147494-20-0)
- Ethyl 4-iodopicolinate (CAS 1650574-67-6)
- 1,3-Dimethyl-5-iodo-2-nitrobenzene (CAS 144991-54-8)
- 2-(2-(Phenylcarbamoyl)hydrazine-1-carbonyl)benzoic acid (CAS 302604-71-3)
- 2-(Heptyloxy)aniline (CAS 55792-44-4)
- 2-Amino-3-bromophenol (CAS 116435-77-9)
- Brivudine Impurity 9 (CAS 59864-10-7)
- 5-Bromo-2-chloro-N-(4-methylthiazol-2-yl)benzamide (CAS 736149-93-2)
- 3-Amino-4-(methylthio)phenol (CAS 155821-45-7)
- (R)-Methyl 3-(((trifluoromethyl)sulfonyl)oxy)-1-trityl-2,5-dihydro-1H-pyrrole-2-carboxylate (CAS 1956437-29-8)
- 1-(1-Ethyl-1H-indol-3-yl)-3-(3-(2-oxopyrrolidin-1-yl)propyl)urea (CAS 899947-39-8)
- 3-Ethyl 5-(2-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamido)ethyl) 2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3,5-dicarboxylate (CAS 135330-18-6)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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