Naphtho[2,3-b]oxirene-2,7(1aH,7aH)-dione CAS 15448-58-5
| CAS No. | 15448-58-5 |
| Molecular Formula | C10H6O3 |
| Molecular Weight | 174.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Naphtho[2,3-b]oxirene-2,7(1aH,7aH)-dione.
CATO supplies Naphtho[2,3-b]oxirene-2,7(1aH,7aH)-dione (CAS 15448-58-5), a certified reference material (molecular formula C10H6O3, MW 174.15 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Naphtho[2,3-b]oxirene-2,7(1aH,7aH)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 174.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6O3 |
| Molecular Weight | 174.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Naphtho Standards
- Naphtho[2,3-d][1,3]dioxole (CAS 269-43-2)
- 2H-Naphtho[1,8-bc]furan-2-one (CAS 5247-85-8)
- 1H-Naphtho[1,2-d][1,2,3]triazole (CAS 233-59-0)
- 1H-Naphtho[1,8-de][1,2,3]triazine (CAS 204-03-5)
- 1H-Naphtho[2,3-d][1,2,3]triazole (CAS 269-12-5)
- 2H-Naphtho[1,2-d][1,2,3]triazole (CAS 233-58-9)
- 1H-Naphtho[1,2-d]imidazole (CAS 233-53-4)
- 2H-Naphtho[1,2-d]imidazole (CAS 23636-20-6)
Recommended Standards
- 6-Ethynylbenzo[d][1,3]dioxole-5-carbaldehyde (CAS 151692-56-7)
- 4-(2,2-Difluoroethoxy)pyridin-2-amine (CAS 1566071-01-9)
- (3R,4S)-4-(methoxycarbonyl)tetrahydrofuran-3-carboxylic acid (CAS 1445590-42-0)
- (3R,6R)-3,6-bis(hydroxymethyl)piperazine-2,5-dione (CAS 15996-17-5)
- (1S,3R)-3-acetamido-N-(5-chloro-4-iodopyridin-2-yl)cyclohexane-1-carboxamide (CAS 2098001-97-7)
- 5-bromo-4-methyl-1H-imidazole-2-carboxylic acid (CAS 1171125-21-5)
- 3-Nitro-n-phenylaniline (CAS 4531-79-7)
- Ilaprazole Impurity 149 (CAS CATO-C4X-1130149)
- Methyl 4-(2-Amino-2-propyl)benzoate (CAS 79361-96-9)
- Montelukast Impurity 4 (CAS 1772578-77-4)
- 4-Chlorobenzo[d]isothiazol-7-amine (CAS 35271-94-4)
- Ethyl 2-(5-methylpyridin-2-yl)pyrimidine-5-carboxylate (CAS 1447607-28-4)
- 2-Amino-4,6-bis(4-fluorophenyl)pyrimidine (CAS 512190-82-8)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
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