Fluconazole Impurity 22 CAS 154534-83-5
| CAS No. | 154534-83-5 |
| Molecular Formula | C10H9F2N4O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Fluconazole Impurity 22 (CAS 154534-83-5), a pharmacopoeial impurity reference standard (molecular formula C10H9F2N4OCl, MW 274.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Fluconazole Impurity 22 (C10H9F2N4OCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Fluconazole Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9F2N4O Cl |
| Molecular Weight | 274.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Fluconazole Standards
- Fluconazole-d4 (CAS 1124197-58-5)
- Fluconazole EP Impurity F (CAS 118689-07-9)
- Fluconazole Impurity 48 (CAS 1222655-38-0)
- Fluconazole Impurity 58 (CAS 123091-15-6 (free base))
- Fluconazole Impurity 19 (CAS 1348664-75-4)
- Fluconazole β-D-glucuronide (CAS 136134-23-1)
- Fluconazole EP Impurity I Bromide (CAS 150168-54-0)
- Fluconazole EP Impurity H (CAS 150194-52-8)
Recommended Standards
- Cefoperazone Impurity 64 (CAS CATO-C4X-114964)
- Misoprostol Impurity 7 (CAS CATO-C4X-14597)
- Zolmitriptan Impurity 43 (CAS CATO-C4X-135143)
- Cyclobutylmethyl 3-piperidinylmethyl etherhydrochloride (CAS 1211505-35-9)
- 5-Chloro-2-(prop-2-yn-1-yloxy)benzoic acid hydrochloride (CAS 2098113-62-1)
- 3,4-(Methylenedioxy)phenylboronic Acid (CAS 94839-07-3)
- tert-butyl 1-methyl-6-(1H-tetrazol-5-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (CAS 1050909-97-1)
- 3,5-Dihydroxy-7-methoxy-2-phenyl-4H-chromen-4-one (CAS 480-14-8)
- tert-Butyl 4-(aminomethyl)-4-methylazepane-1-carboxylate (CAS 1638771-44-4)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com