3-(2,2-Difluoroethoxy)isonicotinonitrile CAS 1545975-09-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1545975-09-4
Molecular FormulaC8H6F2N2O
Molecular Weight184.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2,2-Difluoroethoxy)isonicotinonitrile CAS 1545975-09-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 184.14 g/mol gives 3-(2,2-Difluoroethoxy)isonicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(2,2-Difluoroethoxy)isonicotinonitrile (CAS 1545975-09-4), molecular formula C8H6F2N2O and molecular weight 184.14 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(2,2-Difluoroethoxy)isonicotinonitrile (C8H6F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-(2,2-Difluoroethoxy)isonicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H6F2N2O
Molecular Weight184.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms2

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Why CATO?