Valsartan Impurity 28 CAS 154709-17-8
| CAS No. | 154709-17-8 |
| Molecular Formula | C35H28N4O2 |
| Molecular Weight | 536.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Valsartan Impurity 28 (CAS 154709-17-8), a pharmacopoeial impurity reference standard (molecular formula C35H28N4O2, MW 536.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Valsartan Impurity 28 (C35H28N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Valsartan Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H28N4O2 |
| Molecular Weight | 536.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 4 |
Related Valsartan Standards
- 4-Oxo Valsartan Benzyl Ester (CAS 188240-32-6)
- Valsartan Impurity 150 (CAS CATO-C4X-1057150)
- Valsartan EP Impurity B (CAS 137863-20-8)
- Valsartan Impurity 64 (CAS 143618-44-4)
- Valsartan Impurity 49 (CAS CATO-C4X-105749)
- Valsartan Impurity 25 (CAS 133051-88-4)
- Valsartan Impurity 29 (CAS 124750-51-2)
- Valsartan Impurity 57 (CAS 1353844-77-5)
Recommended Standards
- 1,4-Dihydroxy-5,8-bis((2-(methyl(phenyl)amino)ethyl)amino)anthracene-9,10-dione (CAS 70945-58-3)
- Avibactam Impurity 143 (CAS CATO-C4X-1348143)
- 1,4,5,8-Tetraamino-2,7-bis(4-propylphenoxy)anthracene-9,10-dione (CAS 88600-70-8)
- Nicardipine Impurity 71 (CAS CATO-C4X-171071)
- Sulbactam Impurity 40 (CAS 79702-81-1)
- Lenvatinib Impurity 146 (CAS CATO-C4X-1140146)
- Sudan Black B Impurity 1 (CAS 65322-64-7)
- 2-(Isopropylthio)benzoic acid (CAS 41394-95-0)
- 2-benzyl-3a,6a-dimethyl-octahydropyrrolo[3,4-c]pyrrole dihydrochloride (CAS 2060005-54-9)
- 2-(2H-1,3-benzodioxol-5-yl)-2-methylpropanoic acid (CAS 39053-81-1)
- Methyl 5-Amino-2-chlorobenzoate (CAS 42122-75-8)
- 5-Bromo-3-(bromomethyl)-2-methylpyridine (CAS 1346533-53-6)
- 2,5-Difluoro-N-(furan-2-ylmethyl)aniline (CAS 1019635-16-5)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com