methyl 2,2-difluoro-2-(3-methyl-1H-indazol-6-yl)acetate CAS 1547098-96-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1547098-96-3
Molecular FormulaC11H18F2N2O2
Molecular Weight248.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

methyl 2,2-difluoro-2-(3-methyl-1H-indazol-6-yl)acetate CAS 1547098-96-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 248.27 g/mol gives methyl 2,2-difluoro-2-(3-methyl-1H-indazol-6-yl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies methyl 2,2-difluoro-2-(3-methyl-1H-indazol-6-yl)acetate (CAS 1547098-96-3), a certified reference material (molecular formula C11H18F2N2O2, MW 248.27 g/mol) for analytical method development and quality control.

The molecular framework of methyl 2,2-difluoro-2-(3-methyl-1H-indazol-6-yl)acetate (C11H18F2N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures methyl 2,2-difluoro-2-(3-methyl-1H-indazol-6-yl)acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H18F2N2O2
Molecular Weight248.27 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms2

Related methyl Standards

Recommended Standards

Why CATO?