1-O-(4,4'-Dimethoxytrityl)-2-aminopropan-3-ol CAS 154928-41-3
| CAS No. | 154928-41-3 |
| Molecular Formula | C24H27NO4 |
| Molecular Weight | 393.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 393.48 g/mol gives 1-O-(4,4'-Dimethoxytrityl)-2-aminopropan-3-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-O-(4,4'-Dimethoxytrityl)-2-aminopropan-3-ol (CAS 154928-41-3), a certified reference material (molecular formula C24H27NO4, MW 393.48 g/mol) for analytical method development and quality control.
The molecular framework of 1-O-(4,4'-Dimethoxytrityl)-2-aminopropan-3-ol (C24H27NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H27NO4 |
| Molecular Weight | 393.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 1 |
Related O Standards
- 4,4'-Dimethoxytrityl Chloride (CAS 40615-36-9)
- 5'-O-Dimethoxytrityl-N4-Acetyl-cytidine (CAS 31085-52-6)
- 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (CAS 23669-79-6)
- 5'-O-(Dimethoxytrityl)-5-methyl-3'-deoxyuridine (CAS 114551-15-4)
- 5’-O-(4,4’-Dimethoxytrityl)-3’-β-hydroxythymidine (CAS 112501-53-8)
- 1N-(4,4-Dimethoxytrityl) Biotin (CAS 144095-63-6)
- 5’-O-(Dimethoxytrityl)-5-(1-propynyl)-2’-deoxyuridine (CAS 644962-74-3)
- 5’-O-(Dimethoxytrityl)-5-methyl-2’-O-methyluridine (CAS 115173-73-4)
Recommended Standards
- 2-(1-((((9h-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)cyclohexyl)acetic acid (CAS 1487673-57-3)
- Branaplam, >98% (HPLC) (CAS 1562338-42-4)
- N-Fmoc-N-(cyclohexylmethyl)-glycine (CAS 1374785-49-5)
- 2-Cycloheptyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid (CAS 1695699-56-9)
- 4-Bromo-2-chlorobenzamide (CAS 426265-73-8)
- 1-Cyano-1-methylethyl methanesulfonate (CAS 138999-33-4)
- 2-((6-Benzyl-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N,N-diethylacetamide (CAS 723748-27-4)
- 4-Chloro-3-(difluoromethyl)-2-methoxy-5-methylpyridine (CAS 1806935-52-3)
- N-(2-Chlorophenyl)-2-((6-(furan-2-yl)pyridazin-3-yl)thio)acetamide (CAS 922891-72-3)
- 2-(N-(3-chlorophenyl)methylsulfonamido)butanoic acid (CAS 1218725-15-5)
- N,N-Diethyl-3-(3-piperidinyloxy)anilinehydrochloride (CAS 1220020-70-1)
- (1R,2R,5R)-2-Isopropyl-5-methylcyclohexanamine (CAS 16934-77-3)
- 3-(5-Chloropyridin-2-yl)-3-oxopropanenitrile (CAS 1107053-87-1)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
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