Tretinoin Impurity 9 CAS 15498-86-9
| CAS No. | 15498-86-9 |
| Molecular Formula | C40H56O2 |
| Molecular Weight | 568.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 568.87 g/mol gives Tretinoin Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Tretinoin Impurity 9 (CAS 15498-86-9, C40H56O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tretinoin Impurity 9 (C40H56O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tretinoin Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H56O2 |
| Molecular Weight | 568.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Tretinoin Standards
- Tretinoin lmpurity 20 (CAS 173449-96-2)
- Tretinoin Glucuronide (CAS 401-10-5)
- Tretinoin Impurity 25 (CAS CATO-C4X-196925)
- Tretinoin Impurity 10 (CAS CATO-C4X-196910)
- Tretinoin Impurity 8 (CAS CATO-C4X-19698)
- Tretinoin Impurity 24 (CAS CATO-C4X-196924)
- Tretinoin Impurity 29 (CAS 129454-96-2)
- Tretinoin EP Impurity F (4-Methoxy Retinoic Acid) (CAS 81121-20-2)
Recommended Standards
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- Venetoclax Nitroso Impurity 15 (CAS CATO-C4X-249515)
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