(2-Cyclobutylpyrimidin-5-yl)boronic acid CAS 1551413-91-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1551413-91-2
Molecular FormulaC8H11BN2O2
Molecular Weight178.00 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Cyclobutylpyrimidin-5-yl)boronic acid CAS 1551413-91-2 chemical structure

Description

The occurrence of (2-Cyclobutylpyrimidin-5-yl)boronic acid is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2-Cyclobutylpyrimidin-5-yl)boronic acid (CAS 1551413-91-2), molecular formula C8H11BN2O2 and molecular weight 178.00 g/mol, is a CATO reference standard with documented purity and traceability.

(2-Cyclobutylpyrimidin-5-yl)boronic acid (C8H11BN2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H11BN2O2
Molecular Weight178.00 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Nitrogen Atoms2

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