(2R,5R)-(+)-2,5-diphenylpyrrolidine CAS 155155-73-0

Description

The occurrence of (2R,5R)-(+)-2,5-diphenylpyrrolidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2R,5R)-(+)-2,5-diphenylpyrrolidine (CAS 155155-73-0), molecular formula C16H17N and molecular weight 223.31 g/mol, is a CATO reference standard with documented purity and traceability.

(2R,5R)-(+)-2,5-diphenylpyrrolidine (C16H17N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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