4-(3-bromo-4-fluorophenoxy)benzene-1-sulfonyl chloride CAS 1551735-52-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1551735-52-4
Molecular FormulaC12H7BrClFO3S
Molecular Weight365.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(3-bromo-4-fluorophenoxy)benzene-1-sulfonyl chloride CAS 1551735-52-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 365.60 g/mol gives 4-(3-bromo-4-fluorophenoxy)benzene-1-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(3-bromo-4-fluorophenoxy)benzene-1-sulfonyl chloride (CAS 1551735-52-4), molecular formula C12H7BrClFO3S and molecular weight 365.60 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(3-bromo-4-fluorophenoxy)benzene-1-sulfonyl chloride (C12H7BrClFO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(3-bromo-4-fluorophenoxy)benzene-1-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H7BrClFO3S
Molecular Weight365.60 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF/Cl/Br-containing
Sulfur Atoms1

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