5-(1,3-Dioxolan-2-yl)thiophene-3-carbaldehyde CAS 155294-88-5
| CAS No. | 155294-88-5 |
| Molecular Formula | C8H8O3S |
| Molecular Weight | 184.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(1,3-Dioxolan-2-yl)thiophene-3-carbaldehyde (C8H8O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 5-(1,3-Dioxolan-2-yl)thiophene-3-carbaldehyde (CAS 155294-88-5), a certified reference material (molecular formula C8H8O3S, MW 184.21 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8O3S |
| Molecular Weight | 184.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Sulfur Atoms | 1 |
Related Dioxolan Standards
- 3-(1,3-dioxolan-2-yl)thiophene-2-carbaldehyde (CAS 13250-83-4)
- 5-(1,3-Dioxolan-2-yl)thiophene-2-carbaldehyde (CAS 52509-15-6)
- 4-(1,3-dioxolan-2-yl)cyclohexane-1-carbaldehyde (CAS 2060057-18-1)
- (5-(1,3-Dioxolan-2-yl)furan-2-yl)boronic acid (CAS 1138239-95-8)
- [2-(1,3-dioxolan-2-yl)phenyl] N-(trideuteriomethyl)carbamate (CAS 1219795-12-6)
- 4-(1,3-Dioxolan-2-yl)-5-fluoropyridin-3-ol (CAS 1624260-60-1)
- 2-(1,3-dioxolan-2-yl)-1,3-thiazole-5-carbaldehyde (CAS 1080060-60-1)
- 5-(1,3-dioxolan-2-yl)-1,3-thiazole-2-carbaldehyde (CAS 1803203-53-3)
Recommended Standards
- 1-(4-Fluoro-2-methoxyphenyl)propan-2-ol (CAS 1532339-94-8)
- Methyl 2-(3-methylthiophen-2-yl)-2-oxoacetate (CAS 155299-35-7)
- 4-(Allyloxy)thiophene-2-carboxylic acid (CAS 1512439-65-4)
- 1-(5-Ethoxy-2-fluorophenyl)ethanol (CAS 1554353-36-4)
- (E)-3-(2,3-Dimethoxyphenyl)prop-2-en-1-amine (CAS 1315377-90-2)
- Ethyl 2-bromo-6-cyano-4-(difluoromethyl)benzoate (CAS 1807073-42-2)
- 2-(Pyridin-3-yloxy)pyrimidine-5-carboxylic acid (CAS 927879-20-7)
- 1-(Benzyloxy)-4-(methoxymethyl)benzene (CAS 914296-77-8)
- 3-Methyl-2-(propylsulfonamido)benzoic acid (CAS 926199-89-5)
- 2-Chloro-N'-(3-methoxypropanoyl)acetohydrazide (CAS 1263386-31-7)
- 3-(1-Methyl-1H-pyrazol-4-yl)-1-p-tolyl-propenone (CAS 1003993-48-3)
- (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 64982-62-3)
- Tert-butyl (E)-3-(5-(2-aminoethyl)thiophen-3-yl)acrylate (CAS 124499-25-8)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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