8-(3,5-Difluorophenyl)-1,4-dioxaspiro[4.5]decane CAS 155366-03-3
| CAS No. | 155366-03-3 |
| Molecular Formula | C14H16F2O2 |
| Molecular Weight | 254.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 254.27 g/mol gives 8-(3,5-Difluorophenyl)-1,4-dioxaspiro[4.5]decane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 8-(3,5-Difluorophenyl)-1,4-dioxaspiro[4.5]decane (CAS 155366-03-3), a certified reference material (molecular formula C14H16F2O2, MW 254.27 g/mol) for analytical method development and quality control.
Structurally, 8-(3,5-Difluorophenyl)-1,4-dioxaspiro[4.5]decane (C14H16F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 254.27 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-(3,5-Difluorophenyl)-1,4-dioxaspiro[4.5]decane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H16F2O2 |
| Molecular Weight | 254.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F-containing |
Related Difluorophenyl Standards
- (3,5-Difluorophenyl)(4-fluorobenzyl)sulfane (CAS 1443314-20-2)
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- (3,4-Difluorophenyl)(2-fluorobenzyl)sulfane (CAS 1443327-78-3)
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- (3,5-Difluorophenyl)(3-fluorobenzyl)sulfane (CAS 1443353-15-8)
- (3,5-Difluorophenyl)(2-fluorobenzyl)sulfane (CAS 1443353-39-6)
- N-(2,4-difluorophenyl)-2-(piperidin-1-yl)acetamide (CAS 270086-97-0)
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Recommended Standards
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- (R)-4-ethyl-2,3-dihydro-1H-inden-1-amine (CAS 1213116-41-6)
- [4-ethyl-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]methanol (CAS 1549545-32-5)
- tert-Butyl 8-oxo-2,7-diazaspiro[4.4]nonane-2-carboxylate (CAS 1251009-03-6)
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